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Clarifying Neurodegenerative Features of Late Life Depression: Challenges and Opportunities

Department of Psychiatry Grand Rounds
Presenter Details
Scott Mackin, PhD, Professor of Psychiatry in Residence at the University of California, San Francisco
Scott Mackin, PhD
Professor, Psychiatry
UCSF Weill Institute for Neurosciences

Scott Mackin, PhD, is a clinical neuropsychologist and professor of Psychiatry in Residence at the University of California, San Francisco, and the director of the MIRECC Neuropsychology Fellowship at the San Francisco Veterans Affairs Medical Center. Dr. Mackin’s program of research is focused on identifying structural and functional brain abnormalities associated with depression in older adults and the mechanisms by which these abnormalities lead to accelerated cognitive decline and increased risk of Alzheimer’s disease. 

His work in this area has been funded by the National Institute of Mental Health (NIMH), the Department of Defense (DOD), several philanthropic foundations and private industry. Dr. Mackin is also the lead neuropsychologist for the Brain Health Registry (BHR), an internet research registry developed to facilitate clinical trials for Alzheimer’s Disease and psychiatric disorders. 

Additional Information

For Zoom link and password, please email

Learning Objectives
  1. Describe the incidence of cognitive impairments frequently seen in older adults with depression.
  2. Describe associations of late-life depression with cerebral blood flow abnormalities, reduced cortical thickness, and amyloid deposition as factors contributing to cognitive dysfunction.
  3. Describe the challenges and new opportunities to clarify neurodegenerative features of late life depression.
CME Credit/Disclaimer

All faculty, CME Planning Committee members, and the CME office reviewer have disclosed that they have no financial relationships with commercial interests that would constitute a conflict of interest concerning this CME activity. The University of Arizona College of Medicine – Tucson is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The University of Arizona College of Medicine – Tucson designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

12:00 pm to 1:00 pm
Wednesday, January 13, 2021 - 12:00pm




Jamie Manser
College of Medicine – Tucson
Department of Psychiatry
To request any disability-related accommodations for this event please contact the event coordinator at least three business days prior to the event.