Gene-silencing Injection Reverses Pain in Mice

A study in mice shows certain types of pain can be prevented or reversed without apparent side effects by silencing a gene involved in pain signaling. "It's a beautiful piece of work," said Rajesh Khanna, a neuroscientist who studies pain mechanisms and potential treatments at the University of Arizona College of Pharmacy. Despite successes of gene therapy against rare and life-threatening disorders, few teams have explored genetic approaches to treating pain, he said. "I think this study is going to be our benchmark."