College of Medicine - Phoenix, Department of Translational Neurosciences
When
Where
Health Sciences Education Building, fourth floor, Room B402
435 N. Fifth St., Phoenix, AZ 85004
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Event Description
In this Department of Translational Neurosciences guest seminar, Sean Piantadosi, PhD, a postdoctoral scholar in the Department of Anesthesiology & Pain Medicine at the University of Washington, will deliver a talk titled "Harnessing neuromodulation to investigate amygdala encoding of affect."
This seminar is hybrid.
Presenter Details
Dr. Piantadosi is a translational neuroscientist whose career has been shaped by a desire to understand how affective information is encoded in the brain and how these processes go awry in mood and anxiety disorders. His early training in behavioral pharmacology and rodent stress models led to foundational expertise in identifying translational biomarkers of affective dysfunction, and his graduate work at the University of Pittsburgh bridged human postmortem molecular findings with circuit-level mechanisms of compulsive behavior using in vivo calcium imaging.
During his postdoctoral fellowship at the University of Washington in the laboratory of Dr. Michael Bruchas, he sought to augment these correlative neural imaging approaches with causal manipulations to test mechanistic hypotheses. To accomplish this, he developed deep-brain multiphoton holographic stimulation approaches and a wireless drug-delivery imaging platform to enable precise manipulation and measurement of neuronal ensemble dynamics during behavior. In his future laboratory, he hopes to integrate these techniques to uncover how subcortical microcircuits process affective information to guide behavioral output and how neuromodulatory systems regulate these computations in both healthy and disease states.